Drug delivery in vivo is often affected by physiological and pathological barriers, including hepatic metabolism, renal filtration, immune clearance, and various tissue barriers. In addition, the in vivo application of traditional chemical drugs is often limited by low solubility, short retention time, unsatisfactory bioavailability, and poor targeting ability. Advanced drug delivery systems can give drugs new prescriptions and routes of administration, helping to extend the life cycle of drugs and the inventor's monopoly over the product. Therefore, designing drug delivery systems that can efficiently load drugs and deliver them to the target site has become a major challenge in drug research.
CD BioSciences offers a wide range and depth of biophysical services for drug delivery applications to enhance drug solubility and bioavailability further, prolong retention time, as well as enhance target delivery and cellular uptake while minimizing side effects.
Applications in Drug Delivery System
CD BioSciences provides a scientific basis for constructing drug delivery systems through in-depth studies of biomolecular interactions and drug release mechanisms. We utilize advanced biophysical technologies to accurately measure and evaluate the performance of drug delivery systems to ensure effective drug delivery and release in the body.
Carrier Design
In recent years, nanoparticle-based drug delivery has made remarkable progress in treating diseases. Nanomaterials have excellent biodegradability and biocompatibility and are considered the best carriers for drug delivery systems in biomedical applications. We have a variety of biophysical technologies that can help our clients design more effective drug delivery carriers, which include exosomes, liposomes, or microemulsions in addition to nanoparticles. These carriers are not only biocompatible and stable but also enable targeted delivery and controlled release of drugs. Recently, we have developed nanoparticles encapsulating ribonucleic acid (RNA), which are widely used in medical vaccines.
Study of Mechanisms
Through our biophysical technologies, we can reveal the microscopic mechanisms of drug delivery and transportation, such as the interactions of drug molecules with biological structures such as cell membranes and organelles, as well as the distribution and metabolism of drugs in the body. This information helps clients gain a deeper understanding of drug action mechanisms and provides theoretical support for optimizing drug transport. In addition, our specialized simulation technology can predict and evaluate the relevant mechanisms of drugs in the transport process, further revealing the solubility, stability, and permeability of drugs.
Safety Assessment
Delivery systems can induce biological signaling and soluble factor delivery to regulate cellular behavior and function. We offer specialized biophysical techniques for the safety assessment of drug delivery systems, such as testing nano drug carriers for toxicity, immunogenicity, or in vivo effects on other biomolecules. These results can help to better understand the potential risks of drug delivery systems and develop appropriate safety strategies.
Advantages of Our Services
- Efficient. Our technology platform has state-of-the-art instrumentation to optimize and improve drug delivery systems.
- High accuracy. We utilize specialized biophysical analytical techniques to accurately assess drug delivery systems' performance, including measuring key parameters such as drug release rate, stability, and targeting.
- Personalized service. We can customize the design of drug delivery systems according to the needs of our clients.
Related Services
CD BioSciences, a leader in biophysical analysis, focuses on developing and refining advanced technologies, services, and solutions that make significant contributions to the development of drug delivery systems in the biopharmaceutical field. If you would like more information, please contact us.
For research use only, not
intended for any clinical use.
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