Modeling of Plant Morphogenesis
In order to fully understand morphogenesis in molecular and physical contexts, CD BioSciences aims to model the kinetics of cell division and expansion. In addition, we provide scientific assistance to our clients in assessing the usefulness of models and understanding their relationship to biological data.
Background
The growth of tissues, organs or plants results from the coordinated activities of complex genetic regulatory networks. These processes are controlled differently in specific domains by factors such as master regulatory genes to produce the final design of the tissue or organ. As tissues are physical objects, a thorough analysis of the structure of the growth requires an analysis of its mechanical states, beyond the molecular drivers of growth.
Understanding morphogenesis requires not only assessing changes in the shape of a tissue or organ over time, but also relating it to the dynamics of its components. From a modeling perspective, the processes that shape organs can be broadly divided into three categories: pattern formation, organ expansion and cell division. Models often combine these three to reproduce the final shape of an organ or cell, together with the local expansion patterns that give rise to that shape. Currently, advances in 3D imaging of cell levels and analysis of cell growth have further contributed to the refinement of cell growth models and helped us to understand how plants regulate their cell size.
Fig.1 Models of patterning processes using geometric rules and physical analogies. (Routier-Kierzkowska, 2018)
Dynamic Systems to Model Plant Development
We offer the following methods for modeling plant morphogenesis and growth:
- Modeling phenomena with a one-dimensional topology, such as cell lines or branching structures, based on the L-system.
- Extending the notion of L-systems to two or more dimensions to simulate the structure and morphology of plants.
Our Services
The modeling services we offer include but are not limited to:
- Model of cell-cell interactions during plant morphogenesis
- Descriptive models of growing surfaces
- Modeling a growing shoot apex.
- Modeling a growing leaf.
- Modeling cells and cell division.
- Physically-based model of the shoot apex
- Local determination of apex and primordium centers.
- Calculation of distance on the apex surface.
- Model of the phyllotaxis
- Inhibition models of phyllotaxis.
- Transport-feedback model of phyllotaxis.
- Model of the venation
- Dual transport-feedback models for midvein formation.
- Dual transport-feedback models on a growing cellular template.
Service Features
- Advanced techniques for observing and tracking tissue growth to understand the mechanical properties of cells.
- Quantitative growth data and accurate gene expression data are used to support the hypotheses that form the basis of the models.
- Computer simulations using realistic tissues.
With a team of outstanding experts in the fields of biology, mathematics and physics, CD BioSciences is able to provide modeling services for different types of morphogenesis. Our professional research platform and efficient technical support will greatly accelerate your progress in the field of plant morphogenesis. If you are interested in our services, please contact us for more information.
Reference
- Routier-Kierzkowska, A. L.; Runions, A. Modeling plant morphogenesis: An introduction. Springer. 2018: 165-192.
For research use only, not
intended for any clinical use.
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