The development of biophysical analysis techniques such as microscopic imaging has played a crucial role in the development of the life sciences. With the emergence and refinement of new technologies, cutting-edge research on the structure and dynamic properties of complex biological systems, from biomolecular complexes at the nanoscale, to cells at the micron scale, and even tissues and organs at larger scales, is facing major breakthroughs. These breakthroughs will enable a clearer understanding of how living units perform advanced biological functions at multiple spatial and temporal scales, from cell division to neural connections and even cognition and consciousness in the human brain.

CD BioSciences is committed to providing efficient technical support and scientific services to our clients in the field of neuroscience, including the study of the biophysical mechanisms of neural activity and its plasticity that underpin the higher functions of the brain such as learning, memory and thinking, as well as the biological basis of related mental disorders. Based on an advanced biophysical technology platform, we integrate electrophysiology, photonics, molecular biology and computational simulation to explore at the cellular, network and holistic levels to help our clients bridge the gap between molecular mechanisms and systemic functions.

Fig.1 The composition of the brain. (Carter, 2015)

Our Services

• Whole-Brain Imaging Based on Biophysical Technology
  We have worked to develop new technologies for high-throughput 3D structural and functional imaging and sample processing, as well as new methods for image data processing and analysis to provide efficient whole-brain imaging services to our clients.
• Detection of Neurotransmitters
  We have established a variety of advanced techniques for measuring neurotransmitters in vivo to provide quantitative neurotransmitter analysis services to our clients.
• Analysis of Neurotransmitter Release
  We are dedicated to the development of single-molecule biophysical techniques to help our clients study the molecular mechanisms of neurotransmitter release and the pathogenesis of neurodegenerative diseases.
• Electrophysiological Measurements of Neurons
  We offer multiple methods including extracellular recordings, intracellular recordings and patch-clamp recordings to provide our clients with electrophysiological measurements of neurons.
• Analysis of Synaptic Transmission and Plasticity
  We offer our clients services for synaptic transmission and plasticity analysis by combining electrophysiological techniques with optical techniques.
• Analysis of 3D Neural Morphology
  We provide high-resolution three-dimensional (3D) technologies to help clients capture local and global structural changes in neuronal morphology.
• Visualization of Neural Activity
  We are committed to developing methods for visualizing electrical and biochemical activity in neurons to help customers observe the dynamic events occurring within neurons.
• Structural and Functional Analysis of Neural Circuits
  We have developed a variety of techniques including optical and electron microscopic imaging and big data analysis techniques to provide our clients with structural and functional analysis of neural circuits.
• Biophysical Modeling of Neural Systems
  We are dedicated to helping clients build biophysical models of large-scale neural activity using non-linear dynamical systems theory.

As a pioneer in biophysical analysis, CD BioSciences is committed to developing and refining advanced technologies, services and solutions to make a significant contribution to our clients' research in the field of neuroscience. If you would like more details, please feel free to contact us.

Reference

1. Carter, M.; Shieh, J. C. Guide to research techniques in neuroscience. Academic Press. 2015.

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